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Liquid arrays for decoding the cell surface

At Liquid Biotech, our mission is to advance your research capabilities. We specialize in cutting-edge analyses of cell surface compositions and protein interactions. Explore our comprehensive services today.

Pipette and test plate

Our Mission & Vision

Company Overview

Liquid Biotech is a pioneering biotech startup focused on innovative cell surface analyses.

Our Expertise

We specialize in decoding cell surface compositions and protein binding profiles. Our offerings include reagents and comprehensive data analysis services using pioneering lectin (LiLA) or glycan (LiGA) display technologies. We aim to transform research by identifying and quantifying biological interactions

Milestones

Key Accomplishments

Research Papers

Published Work

We have collaborated on multiple research papers showcasing our innovative approaches in biotechnology and cell analysis.

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1. E. J. Carpenter, C. Peng, S. Wang, R. Greiner, R. Derda, “Atom-level Machine Learning of Protein-glycan Interactions and Cross-chiral Recognition in Glycobiology” Science Advances in press, 2025, https://doi.org/10.1101/2025.01.21.633632

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2. G. M. Lima, Z. Jame-Chenarboo, M. Sojitra, S. Sarkar, E. J. Carpenter, C. Y. Yang, E. Schmidt, J. Lai, A. Atrazhev, D. Yazdan, C. Peng, E. A. Volker, R. Ho, G. Monteiro, R. Lai, L. K. Mahal, M. S. Macauley, R. Derda, “The liquid lectin array detects compositional glycocalyx differences using multivalent DNA-encoded lectins on phage“, Cell Chem. Biol. (2024)

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3. M.Sojitra, E. N. Schmidt, G. M. Lima, E. J. Carpenter, K. A. McCord, A. Atrazhev, M. S. Macauley, R. Derda, “Measuring carbohydrate recognition profile of lectins on live cells using liquid glycan array (LiGA)Nat Protoc. (2024)

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4. Chih-Lan Lin, Mirat Sojitra, Eric J. Carpenter, Ellen S. Hayhoe, Susmita Sarkar, Elizabeth A. Volker, Chao Wang, Duong T. Bui, Loretta Yang, John S. Klassen, Peng Wu, Matthew S. Macauley, Todd L. Lowary & Ratmir Derda “Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arraysNat. Comm.  14, 5237 (2023)

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5. Eric J. Carpenter, Shaurya Seth, Noel Yue, Russell Greiner, and Ratmir Derda* “GlyNet: A Multi-Task Neural Network for Predicting Protein-Glycan Interactions“, Chem. Sci., 2022,13, 6669-6686 and  BioRxiv Preprint 2021, YouTube videos: OneGlycan1246ProteinsOneProtein599GlycansOneProtein4160NewGlycans

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6. Mirat Sojitra, Susmita Sarkar, Jasmine Maghera, Emily Rodrigues, Eric J. Carpenter, Shaurya Seth, Daniel Ferrer Vinals, Nicholas J. Bennett, Revathi Reddy, Amira Khalil, Xiaochao Xue, Michael R. Bell, Ruixiang Blake Zheng, Ping Zhang, Corwin Nycholat, Justin J. Bailey, Chang-Chun Ling, Todd L. Lowary, James C. Paulson, Matthew S. Macauley & Ratmir Derda* “Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage“, Nature Chemical Biology 2021, 17, 806–816.

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Patents

Innovative Solutions

Our unique technologies are protected by patents, ensuring our advancements contribute uniquely to the field.

Partnerships

Collaborative Efforts

We have established strong partnerships with leading research institutions, enhancing our capability to drive biotech innovations.

Client Satisfaction

Feedback Received

Our clients consistently report high satisfaction rates, attributing our success to reliable services and expert analysis.

Service Expansion

Broader Scope

We’ve successfully expanded our service offerings, adapting to the evolving needs of the biotech community.

Innovative Methods

Our Approach

We leverage advanced lectin and glycan display technologies to deliver comprehensive protein binding profile analyses.

Data Analysis

Our data processing services are tailored to ensure that all findings are accurate and useful for your research needs.

Cell Surface Profiling

We utilize state-of-the-art techniques for detailed profiling of cell surfaces to uncover critical biological information.

Analyze any type of molecule

Clients have the option to attach any chemically modified molecule (e.g. biotinylated molecules), enabling precise testing of various interactions and responses.

Ready to get started? Fill out our service request form and let us know what you're looking for!
Don’t hesitate to reach out if you have any questions.

liquidbiotech.net

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